100+ Grey's Anatomy Trivia Questions & Answers

Question: Who is known as "McDreamy"?

Answer: Derek Shepherd

Question: Which character was nicknamed "007"?

Answer: George O'Malley

Question: Who stabbed Alex Karev with an epi?

Answer: Cristina Yang

Question: Who did Cristina Yang marry?

Answer: Owen Hunt

Question: Who was Meredith's mother?

Answer: Ellis Grey

Question: Who is Lexie Grey's half-sister?

Answer: Meredith Grey

Question: Who was Derek Shepherd's first wife?

Answer: Addison Montgomery

Question: Who played Addison Montgomery?

Answer: Kate Walsh

Question: Who was nominated for a Harper Avery?

Answer: Cristina Yang

Question: Who is known for saying "Seriously"?

Answer: Meredith Grey

Question: Who did Izzie Stevens marry?

Answer: Alex Karev

Question: Who was the Chief of Surgery at Seattle Grace?

Answer: Richard Webber

Question: Who played Alex Karev?

Answer: Justin Chambers

Question: Who did April Kepner marry?

Answer: Jackson Avery

Question: Who played Callie Torres?

Answer: Sara Ramirez

Question: Who was George O'Malley's first girlfriend?

Answer: Callie Torres

Question: Who was the original head of cardio at Seattle Grace?

Answer: Preston Burke

Question: Who did Mark Sloan have a child with?

Answer: Callie Torres

Question: Who played Lexie Grey?

Answer: Chyler Leigh

Question: Who was Meredith's first roommate?

Answer: Izzie Stevens

Question: Who did Owen Hunt date before marrying Cristina?

Answer: Teddy Altman

Question: Who was nicknamed "McSteamy"?

Answer: Mark Sloan

Question: Who did George O'Malley cheat on Callie Torres with?

Answer: Izzie Stevens

Question: Who played Arizona Robbins?

Answer: Jessica Capshaw

Question: Who was known as "Bambi"?

Answer: George O'Malley

Question: Who was the first doctor shot in the episode "Sanctuary"?

Answer: Reed Adamson

Question: What animal did Izzie save in the season opener?

Answer: A deer

Question: Who gets their eyebrows waxed off on their wedding day?

Answer: Cristina Yang

Question: Who was stabbed by an icicle in the season opener?

Answer: Cristina Yang

Question: What was the name of the ball in the episode "Dream A Little Dream Of Me"?

Answer: Fire and Ice

Question: What sentence does Meredith say at the end of episode 23 "Readiness is All"?

Answer: "That's how the good things come too."

Question: What song played during Cristina and Burke's first date?

Answer: "No Sleep Tonight" by The Faders

Question: What tragic event happens to George in the episode "Now or Never"?

Answer: He gets hit by a bus

Question: What type of surgery did George perform in an elevator?

Answer: Heart surgery

Question: What was the name of the clinic Izzie opened?

Answer: Denny Duquette Memorial Clinic

Question: Who is the first patient treated in the episode "A Hard Day's Night"?

Answer: Katie Bryce

Question: What color dress did Izzie wear to the prom?

Answer: Dark pink

Question: Who does Meredith see in her afterlife?

Answer: Ellis Grey

Question: Who did April Kepner accidentally kill?

Answer: A patient with a throat injury

Question: What organ did Meredith donate to her father?

Answer: Liver

Question: Who was the second doctor shot in "Sanctuary"?

Answer: Alex Karev

Question: What did Cristina keep telling Meredith in the episode "Flight"?

Answer: "I can't find my shoe!"

Question: What did Derek Shepherd call Meredith Grey when they first met?

Answer: The girl in the bar

Question: Who did George O'Malley save during a ferry boat accident?

Answer: A young boy

Question: What did Meredith Grey's mother suffer from?

Answer: Alzheimer's disease

Question: Who was the first intern to perform surgery in an elevator?

Answer: George O'Malley

Question: Who was Meredith Grey's first patient?

Answer: Katie Bryce

Question: What was the name of the hospital Derek Shepherd moved to after Seattle Grace?

Answer: Seattle Grace Mercy West

Question: Who did Cristina Yang operate on during the shooting?

Answer: Derek Shepherd

Question: What was the name of the episode where Meredith and Derek adopt Zola?

Answer: "This Magic Moment"

Question: Who did Meredith Grey marry?

Answer: Derek Shepherd

Question: Who did Cristina Yang have an on-and-off relationship with?

Answer: Preston Burke

Question: Who did Alex Karev date before marrying Jo?

Answer: Izzie Stevens

Question: Who did Mark Sloan have a long-term affair with?

Answer: Addison Montgomery

Question: Who did Callie Torres marry after George O'Malley?

Answer: Arizona Robbins

Question: Who did April Kepner have a child with?

Answer: Jackson Avery

Question: Who did Owen Hunt marry after Cristina Yang?

Answer: Amelia Shepherd

Question: Who did Lexie Grey have a serious relationship with?

Answer: Mark Sloan

Question: Who did Richard Webber cheat on his wife with?

Answer: Ellis Grey

Question: Who did Jo Wilson date before Alex Karev?

Answer: Jason Myers

Question: Who did Amelia Shepherd marry after Owen Hunt?

Answer: Link

Question: Who did Teddy Altman have a child with?

Answer: Owen Hunt

Question: Who did George O'Malley have an affair with?

Answer: Izzie Stevens

Question: Who did Bailey date before marrying Ben?

Answer: Tucker Jones

Question: Who did Addison Montgomery date after Derek Shepherd?

Answer: Mark Sloan

Question: Who did Meredith Grey date before Derek Shepherd?

Answer: Finn Dandridge

Question: Who did April Kepner date before marrying Jackson Avery?

Answer: Matthew Taylor

Question: Who did Cristina Yang date after Preston Burke?

Answer: Owen Hunt

Question: Who did Mark Sloan date before his death?

Answer: Lexie Grey

Question: Who did Richard Webber marry after Adele?

Answer: Catherine Avery

Question: Who did Arizona Robbins date after Callie Torres?

Answer: Eliza Minnick

Question: Who did Alex Karev marry after Jo Wilson?

Answer: No one

Question: Who did Derek Shepherd date before Meredith Grey?

Answer: Addison Montgomery

Question: Who did Owen Hunt date after his divorce from Cristina?

Answer: Teddy Altman

Question: Who did Amelia Shepherd date after her divorce from Owen?

Answer: Link

Question: What is the name of the hospital in "Grey's Anatomy"?

Answer: Seattle Grace Hospital

Question: Who created "Grey's Anatomy"?

Answer: Shonda Rhimes

Question: What is the theme song of "Grey's Anatomy"?

Answer: "Cosy in the Rocket" by Psapp

Question: What specialty does Cristina Yang pursue?

Answer: Cardiothoracic surgery

Question: What nickname does Derek Shepherd give to Meredith Grey?

Answer: Mer

Question: What specialty does Alex Karev switch to?

Answer: Pediatrics

Question: What does "McDreamy" refer to?

Answer: Derek Shepherd

Question: What specialty does Mark Sloan practice?

Answer: Plastic surgery

Question: What specialty does Miranda Bailey practice?

Answer: General surgery

Question: What city is "Grey's Anatomy" set in?

Answer: Seattle

Question: What specialty does Addison Montgomery practice?

Answer: Neonatal surgery

Question: What specialty does Callie Torres practice?

Answer: Orthopedic surgery

Question: What is the name of the bar frequented by the doctors?

Answer: Joe's Bar

Question: What is Meredith Grey's dog's name?

Answer: Doc

Question: What is the name of Meredith's half-sister who becomes a doctor?

Answer: Lexie Grey

Question: What is the name of the ferryboat accident episode?

Answer: "Walk on Water"

Question: What is the name of Derek and Meredith's first child?

Answer: Zola

Question: What was the original name of Seattle Grace Hospital?

Answer: Seattle Grace Mercy West Hospital

Question: What specialty does Richard Webber practice?

Answer: General surgery

Question: What is the name of the hospital's board chairman?

Answer: Harper Avery

Question: What does "McSteamy" refer to?

Answer: Mark Sloan

Question: What specialty does Jo Wilson practice?

Answer: General surgery

Question: When was the 18th season announced?

Answer: May 10th, 2021

Question: What was the name of the "surgery" doll that Ellis gave to Meredith?

Answer: Anatomy Jane

Question: Who was responsible for the hospital shooting in season 6?

Answer: Gary Clark

Question: What is Derek's signature line?

Answer: "It's a beautiful day to save lives."